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程崟家老师简介
程崟家老师简介

姓    名:程崟家

职    称:副教授

单    位:永利集团88304官网化学与材料科学学院

学科专业:高分子化学和物理

研究方向:生物医用高分子材料

学者简介

程崟家(1988-),女,博士,副教授2011年毕业于衡阳南华大学,获化工制药专业学士学位;2011-2016在武汉大学硕博连读,获高分子化学与物理专业博士学位。20168月起,于永利集团88304官网化学与材料科学学院任教。主要从事智能型药物载体的设计、构建及其在生物医用领域的应用研究。已在BiomaterialsJournal of Controlled Release; ACS Applied Materials & InterfacesPolymer ChemistryACS Biomaterials Science & Engineering等国际SCI刊物上公开发表SCI论文数篇;获批两项国家发明专利;曾获得教育部武汉大学研究生奖学金、唐敖庆化学奖学金等荣誉。

主持的科研项目

1. 国家自然科学基金面上项目(52173295),特洛伊木马型仿生纳米复合材料的构建及在肿瘤多模态精准诊疗中的应用2022-2025

2. 国家自然科学基金青年项目(51703251),多功能富勒烯/介孔硅复合纳米药物控释系统的构建及其肿瘤诊疗的研究,2018-2020

3. 中央高校基本科研业务费专项资金自科一般项目(CZY17003),功能肽修饰的纳米复合体系应用于肿瘤的联合诊疗,2017-2018

已授权专利

1. 程崟家,秦四勇,张爱清。一种聚集诱导发光多肽胶束型诊断试剂及其在近红外区域生物成像中的应用,2022.05.17,中国,ZL202110709792.X

2. 程崟家,黎永秀,秦四勇,张爱清。一种酶敏感型多肽胶束型诊断试剂及其在制备抗肿瘤药物中的应用,2022.05.30,中国,ZL202110540998.4

近年来发表的部分论文

1. He Y., Chen Q.W., Yu J. X., Qin S. Y., Liu W. L., Ma Y. H., Chen X. S., Zhang A. Q., Zhang X. Z., Cheng Y. J.# Yeast cell membrane-camouflaged PLGA nanoparticle platform for enhanced cancer therapy. J Control Release, 2023, 359: 347-358.

2. Cheng Y. J.#, Qin S. Y., Liu W L, et al. Dual-Targeting Photosensitizer-Peptide Amphiphile Conjugate for Enzyme-Triggered Drug Delivery and Synergistic Chemo-Photodynamic Tumor Therapy. Adv. Mater. Interfaces, 2020, 7(19): 2000935. (Inside Cover)

3. Cheng Y. J. #, Hu J. J., Qin S. Y., et al. Recent advances in functional mesoporous silica-based nanoplatforms for combinational photo-chemotherapy of cancer. Biomaterials, 2020, 232, 119738.

4. Cheng Y. J.#, Qin S. Y., Ma Y. H., et al. Super-pH-Sensitive Mesoporous Silica Nanoparticle-Based Drug Delivery System for Effective Combination Cancer Therapy. ACS Biomaterials Science & Engineering, 2019, 5 (4), 1878-1886.

5. Cheng Y. J. #, Zhang A. Q., Hu J. J., et al. Multifunctional Peptide-Amphiphile End-Capped Mesoporous Silica Nanoparticles for Tumor Targeting Drug Delivery. ACS Applied Materials & Interfaces, 2017, 9, 2093-2103.

6. Cheng Y. J. #, Luo G. F., Zhu J. Y., et al. Enzyme-induced and tumor-targeted drug delivery system based on multifunctional mesoporous silica nanoparticles. ACS Applied Materials & Interfaces, 2015, 7, 9078-9087.

7. Cheng Y. J., Cheng H., Zhao X., et al. Self-assembled micelles of a multi-functional amphiphilic fusion (MFAF) peptide for targeted cancer therapy. Polymer Chemistry, 2015, 6, 3512-3520.

8. Xu X. D.*, Cheng Y. J.* (共同第一作者), Wu J., et al. Smart and hyper-fast responsive polyprodrug nanoplatform for targeted cancer therapy. Biomaterials, 2015, 76, 238-249.

9. Cheng Y. J., Zeng X., Cheng D. B., et al. Functional mesoporous silica nanoparticles (MSNs) for highly controllable drug release and synergistic therapy. Colloids and Surfaces B: Biointerfaces, 2016, 145, 217-225.


通讯地址:武汉市洪山区民族大道182

联系方式:18707130927  

E-mailChengYJ@mail.scuec.edu.cn